Tiotropium and exercise training in COPD patients: Effects on dyspnea and exercise tolerance
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چکیده
منابع مشابه
Tiotropium and exercise training in COPD patients: Effects on dyspnea and exercise tolerance
BACKGROUND Exercise training improves exercise tolerance in chronic obstructive pulmonary disease (COPD). Tiotropium 18 microg once daily induces sustained bronchodilation throughout the day and reduces hyperinflation, one of the pathophysiological factors contributing to exertional dyspnea in COPD patients. AIM To determine whether tiotropium enhances the effects of exercise training in pati...
متن کاملEffects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD.
The aim of this study was to test the hypothesis that use of tiotropium, a new long-acting anticholinergic bronchodilator, would be associated with sustained reduction in lung hyperinflation and, thereby, would improve exertional dyspnoea and exercise performance in patients with chronic obstructive pulmonary disease. A randomised, double-blind, placebo-controlled, parallel-group study was cond...
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Dyspnea, a symptom limiting exercise capacity in patients with COPD, is associated with central perception of an overall increase in central respiratory motor output directed preferentially to the rib cage muscles. On the other hand, disparity between respiratory motor output, mechanical and ventilatory response of the system is also thought to play an important role on the increased perception...
متن کاملBenefits of short inspiratory muscle training on exercise capacity, dyspnea, and inspiratory fraction in COPD patients
Abstract: Static lung hyperinflation has important clinical consequences in patients with chronic obstructive pulmonary disease (COPD). Given that most of these patients have respiratory and peripheral muscle weakness, dyspnea and functional exercise capacity may improve as a result of inspiratory muscle training (IMT). The present study is designed to investigate the benefits of a short outpat...
متن کاملInspiratory muscle training in patients with COPD: effect on dyspnea, exercise performance, and quality of life.
OBJECTIVE The aim of the study was to assess the effect of target-flow inspiratory muscle training (IMT) on respiratory muscle function, exercise performance, dyspnea, and health-related quality of life (HRQL) in patients with COPD. PATIENTS AND METHODS Twenty patients with severe COPD were randomly assigned to a training group (group T) or to a control group (group C) following a double-blin...
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ژورنال
عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease
سال: 2008
ISSN: 1178-2005
DOI: 10.2147/copd.s3935